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Publications

Imetelstat

All Publications

Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis

Clinical Imetelstat: MF Imetelstat

Journal of Clinical Oncology 2021

Mascarenhas, et al.

Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study

Clinical Imetelstat: MDS Imetelstat

Journal of Clinical Oncology 2020

Steensma, et al.

Imetelstat Demonstrates an Acceptable Safety Profile in Myeloid Malignancies

Clinical Imetelstat: MDS Imetelstat

Mascarenhas, et al.

Treatment with Imetelstat Provides Durable Transfusion Independence (TI) in Heavily Transfused Non-del(5q) Lower Risk MDS (LR-MDS) Relapsed/Refractory (R/R) to Erythropoiesis Stimulating Agents (ESAs)

Clinical Imetelstat: MDS Imetelstat

Platzbecker, et al.

IMerge: A Phase 3 Study to Evaluate Imetelstat in Transfusion-Dependent Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndromes (MDS) that is Relapsed/Refractory to Erythropoiesis-Stimulating Agent (ESA) Treatment

Clinical Imetelstat: MDS Imetelstat

Platzbecker, et al.

Potential Disease-Modifying Activity of Imetelstat Demonstrated By Reduction in Cytogenetically Abnormal Clones and Mutation Burden Leads to Clinical Benefits in Relapsed/Refractory Myelofibrosis Patients

Clinical Imetelstat: MF Imetelstat

Mascarenhas, et al.

Telomerase Activity, Telomere Length and hTERT Expression Correlate with Clinical Outcomes in Higher-Risk Myelofibrosis (MF) Relapsed/Refractory (R/R) to Janus Kinase Inhibitor Treated with Imetelstat

Clinical Imetelstat: MF Imetelstat

Mascarenhas, et al.

Favorable Overall Survival with Imetelstat Treatment Correlates with Other Clinical Benefits in Intermediate-2 or High-Risk Myelofibrosis Relapsed/Refractory to Janus Kinase Inhibitor

Clinical Imetelstat: MF Imetelstat

Mascarenhas, et al.

Correlation Analyses of Imetelstat Exposure with Pharmacodynamic Effect, Efficacy and Safety in a Phase 2 Study in Patients with Higher-risk Myelofibrosis Refractory to Janus Kinase Inhibitor Identified an Optimal Dosing Regimen for Phase 3 Study

Clinical Imetelstat: MF Imetelstat

Mascarenhas, et al.

Imetelstat Treatment Results in Clinical Benefits, Including Improved Overall Survival, in Patients with Higher-Risk Triple Negative Myelofibrosis Relapsed/Refractory to Janus Kinase Inhibitors (JAKi)

Clinical Imetelstat: MF Imetelstat

Kiladjian, et al.

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